Our Group
examines how changes in neurons and their connections mediate learning. We focus on motivated learning which underlies addiction and associated behaviours. This work complements Psychology collaborators who investigate the behavioural effects of manipulating these circuits.
Our Research
uses a combination of advanced neurophysiological techniques including electrophysiology, optogenetics, and fluorescent calcium imaging to determine how brain regions involved in motivated behaviours are connected on a cellular level, and how learning or drugs of abuse changes these connections.
Our Goal
is to identify and validate therapeutic targets for the treatment of the aberrant learning processes that underly conditions such as addiction, obesity, and post traumatic stress disorder. Ultimately, we hope to use our knowledge of the underlying connections to modify circuits to support abstinence and reduce to risk of relapse.
Group Leader and a Senior Lecturer
John obtained his PhD from Northwestern University in 1999 in the lab of John Disterhoft where he examined how aging and learning change the electrical excitability of neurons in the hippocampus. He underwent post-doctoral training with Pankaj Sah at the John Curtin School of Medical Research and the Queensland Brain Institute, where he became a Smart State Fellow. There he made key contributions to our understanding of neuromodulatory transmitter mediated intracellular calcium signaling, and its effect on neuronal excitability and connectivity.
In 2012 Dr Power moved to UNSW Sydney and founded the Neuroplasticity in Memory and Addiction Group within the Translational Neuroscience Facility.
Twitter: @johnp_why_me
LinkedIn: www.linkedin.com/in/john-power-8701ab92
UNSW Webpages: Staff Page and Research Group
PhD Student
Examining the Role of Basolateral Amygdala Cellular Plasticity in Instrumental Learning Processes
PhD Student
Defining the functional connectivity of the paraventricular thalamus.
PhD Student
Circuit mapping of nucleus accumbens → ventral pallidum → lateral hypothalamus pathway in alcohol self-administration and relapse.
Honours Student
A day in the life